SAN FRANCISCO, CALIFORNIA - DECEMBER 04: (L-R) Sandra Upson, Features Editor, WIRED and Dr. Eric Topol, EVP, Scripps Research speak onstage during "The Science of Super Agers" at WIRED's The Big Interview 2025 at The Midway SF on December 04, 2025 in San Francisco, California. (Photo by Kimberly White/Getty Images for Wired)